[HTML][HTML] Recombinant envelope protein-based enzyme immunoassay for IgG antibodies is comparable to neutralization tests for epidemiological studies of dengue …

ES de Oliveira Rocha, JG de Oliveira… - Journal of virological …, 2013 - Elsevier
Dengue virus (DENV) is the most prevalent arbovirus in the world, found mainly in tropical
regions. As clinical manifestations present frequently as nonspecific febrile illness,
laboratory diagnosis is essential to confirm DENV infections and for epidemiological studies.
Recombinant envelope (E) antigens of four serotypes of DENV were used to develop an
immunoglobulin G enzyme-linked immunosorbent assay (IgG-ELISA). To evaluate the IgG-
ELISA, a panel of serum samples that had been tested previously by a plaque reduction …
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